Armstrong, 34, set his record winning streak after he had been diagnosed with cancer and given less than a 50 percent chance of survival.

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"I was thrilled to learn late last night of Lance's decision to run the New York City marathon," Wittenberg said in a statement. "A bit like winning the lottery after you thought you had lost.

"Lance epitomises both the American spirit and the spirit of the marathon and it is no surprise that his drive, motivation and focus lead him to his next challenge."